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Glycerol is a specific bowel mucosa irritant and when introduced in very dilute solution serves to induce peristalsis. His favorite device was an enema machine "just like one I saw in Germany" that could run fifteen gallons of water through an unfortunate bowel in a matter of seconds. Archived from the original on 7 August In the late 20th century the microenema was invented, this being a disposable squeeze bottle with contents that cause the body to draw water into the colon, e. Noting that deaths have been reported from alcohol poisoning via enemas,  an alcohol enema can be used to very quickly instill alcohol into the bloodstream, absorbed through the membranes of the colon. Retrieved 13 March
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In the late 19th century Dr. Johns Hopkins University Press , pp. A kilogram pound brass statue of a syringe enema bulb held aloft by three angels stands in front of the "Mashuk" spa in the settlement of Zheleznovodsk in Russia. In the Gerson therapy , coffee enemas are administered.
Description: The Senate Intelligence Committee report on CIA torture documented instances of enemas being used by the Central Intelligence Agency in order to ensure "total control" over detainees. Its effectiveness varies considerably, some individuals experiencing complete control of incontinence but others reporting little or no benefit. Bowel stimulating enemas usually consist of water, which works primarily as a mechanical stimulant, or they may be made up of water with baking soda sodium bicarbonate  or water with a mild hand soap dissolved in it. Mouthwash Toothpaste Ointment Oral spray. Archives of Internal Medicine.